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Deficiency of MMP1a Collagenase Suppresses Development of Atherosclerosis in Mice: Translational Implications for Human Coronary Artery Disease

OBJECTIVE: Destruction of arterial collagen allows monocyte and macrophage infiltration leading to atherosclerotic plaque formation, but it is not clear what role the MMP1 collagenase plays in this process in vivo. To define the specific contribution of MMP1 to atherosclerotic plaque burden and path...

詳細記述

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書誌詳細
出版年:Arterioscler Thromb Vasc Biol
主要な著者: Fletcher, Elizabeth K., Wang, Yanling, Flynn, Laura K., Turner, Susan E., Rade, Jeffrey J., Kimmelstiel, Carey D., Gurbel, Paul A., Bliden, Kevin P., Covic, Lidija, Kuliopulos, Athan
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062306/
https://ncbi.nlm.nih.gov/pubmed/33761760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315837
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