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Noncanonical Matrix Metalloprotease 1–Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis

OBJECTIVE—: Protease-activated receptor-1 (PAR1) is classically activated by thrombin and is critical in controlling the balance of hemostasis and thrombosis. More recently, it has been shown that noncanonical activation of PAR1 by matrix metalloprotease-1 (MMP1) contributes to arterial thrombosis....

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Библиографические подробности
Опубликовано в: :Arterioscler Thromb Vasc Biol
Главные авторы: Rana, Rajashree, Huang, Tianfang, Koukos, Georgios, Fletcher, Elizabeth K., Turner, Susan E., Shearer, Andrew, Gurbel, Paul A., Rade, Jeffrey J., Kimmelstiel, Carey D., Bliden, Kevin P., Covic, Lidija, Kuliopulos, Athan
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076425/
https://ncbi.nlm.nih.gov/pubmed/29622563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310967
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