Smooth Muscle Cell Specific Pyruvate Kinase M2 Promotes SMC Phenotypic Switching and Neointimal Hyperplasia

OBJECTIVE: The role of glycolytic enzyme pyruvate kinase M2 (PKM2) in SMC phenotype switching and neointimal hyperplasia is poorly understood. We determined the role of PKM2 in SMC phenotype switching and neointimal hyperplasia. APPROACH AND RESULTS: We show that PKM2 is expressed in the SMC-rich ne...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arterioscler Thromb Vasc Biol
Egile Nagusiak: Jain, Manish, Dhanesha, Nirav, Doddapattar, Prakash, Nayak, Manasa K., Guo, Liang, Cornelissen, Anne, Lentz, Steven R., Finn, Aloke V., Chauhan, Anil K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062279/
https://ncbi.nlm.nih.gov/pubmed/33691477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.121.316021
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