Smooth Muscle Cell Specific Pyruvate Kinase M2 Promotes SMC Phenotypic Switching and Neointimal Hyperplasia

OBJECTIVE: The role of glycolytic enzyme pyruvate kinase M2 (PKM2) in SMC phenotype switching and neointimal hyperplasia is poorly understood. We determined the role of PKM2 in SMC phenotype switching and neointimal hyperplasia. APPROACH AND RESULTS: We show that PKM2 is expressed in the SMC-rich ne...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Jain, Manish, Dhanesha, Nirav, Doddapattar, Prakash, Nayak, Manasa K., Guo, Liang, Cornelissen, Anne, Lentz, Steven R., Finn, Aloke V., Chauhan, Anil K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062279/
https://ncbi.nlm.nih.gov/pubmed/33691477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.121.316021
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge