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Local Stabilization of Subunit–Subunit Contacts Causes Global Destabilization of Hepatitis B Virus Capsids
Development of antiviral molecules that bind virion is a strategy that remains in its infancy, and the details of their mechanisms are poorly understood. Here we investigate the behavior of DBT1, a dibenzothiazepine that specifically interacts with the capsid protein of hepatitis B virus (HBV). We f...
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| I publikationen: | ACS Chem Biol |
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| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8062159/ https://ncbi.nlm.nih.gov/pubmed/32369333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00320 |
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