Testing for non-inferior mortality: a systematic review of non-inferiority margin sizes and trial characteristics

OBJECTIVE: To describe the size and variability of non-inferiority margins used in non-inferiority trials of medications with primary outcomes involving mortality, and to examine the association between trial characteristics and non-inferiority margin size. DESIGN: Systematic review. DATA SOURCES: M...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMJ Open
Päätekijät: Pong, Sandra, Urner, Martin, Fowler, Robert A, Mitsakakis, Nicholas, Seto, Winnie, Hutchison, James S, Science, Michelle, Daneman, Nick
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Publishing Group 2021
Aiheet:
Research Methods
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061825/
https://ncbi.nlm.nih.gov/pubmed/33879485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-044480
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