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Adaptive non-inferiority margins under observable non-constancy

A central assumption in the design and conduct of non-inferiority trials is that the active-control therapy will have the same degree of effectiveness in the planned non-inferiority trial as in the prior placebo-controlled trials used to define the non-inferiority margin. This is referred to as the...

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Detalhes bibliográficos
Publicado no:Stat Methods Med Res
Main Authors: Hanscom, Brett, Hughes, James P, Williamson, Brian D, Donnell, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128326/
https://ncbi.nlm.nih.gov/pubmed/30293490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280218801134
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