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The Impact of the Underlying Risk in Control Group and Effect Measures in Non-Inferiority Trials With Time-to-Event Data: A Simulation Study
BACKGROUND: We designed a simulation study to assess how the conclusions of a non-inferiority trial (NIT) will change if the observed risk is different from the expected risk. METHODS: We simulated Weibull distribution time-to-event data with a true hazard ratio (HR) being equal or close to 1. The e...
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| Vydáno v: | J Clin Med Res |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elmer Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5862084/ https://ncbi.nlm.nih.gov/pubmed/29581799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14740/jocmr3349e |
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