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Palmitoylation of Hedgehog proteins by Hedgehog acyltransferase: roles in signalling and disease
Hedgehog acyltransferase (Hhat), a member of the membrane-bound O-acyltransferase (MBOAT) family, catalyses the covalent attachment of palmitate to the N-terminus of Hedgehog proteins. Palmitoylation is a post-translational modification essential for Hedgehog signalling. This review explores the mec...
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| Publicado en: | Open Biol |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8061759/ https://ncbi.nlm.nih.gov/pubmed/33653085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200414 |
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