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Advances in Cancer Treatment by Targeting the Neddylation Pathway

Developmental down-regulation protein 8 (NEDD8), expressed by neural progenitors, is a ubiquitin-like protein that conjugates to and regulates the biological function of its substrates. The main target of NEDD8 is cullin-RING E3 ligases. Upregulation of the neddylation pathway is closely associated...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Gai, Wenbin, Peng, Zhiqiang, Liu, Cui Hua, Zhang, Lingqiang, Jiang, Hong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060460/
https://ncbi.nlm.nih.gov/pubmed/33898451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.653882
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