Development and evaluation of physiologically based pharmacokinetic drug-disease models for predicting captopril pharmacokinetics in chronic diseases

The advancement in the processing speeds of computing machines has facilitated the development of complex physiologically based pharmacokinetic (PBPK) models. These PBPK models can incorporate disease-specific data and could be used to predict pharmacokinetics (PK) of administered drugs in different...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Rasool, Muhammad F., Ali, Shazia, Khalid, Sundus, Khalid, Ramsha, Majeed, Abdul, Imran, Imran, Saeed, Hamid, Usman, Muhammad, Ali, Mohsin, Alali, Amer S., AlAsmari, Abdullah F., Ali, Nemat, Asiri, Ali Mohammed, Alasmari, Fawaz, Alqahtani, Faleh
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060346/
https://ncbi.nlm.nih.gov/pubmed/33883647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88154-2
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