Development and evaluation of physiologically based pharmacokinetic drug-disease models for predicting captopril pharmacokinetics in chronic diseases

The advancement in the processing speeds of computing machines has facilitated the development of complex physiologically based pharmacokinetic (PBPK) models. These PBPK models can incorporate disease-specific data and could be used to predict pharmacokinetics (PK) of administered drugs in different...

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Vydáno v:Sci Rep
Hlavní autoři: Rasool, Muhammad F., Ali, Shazia, Khalid, Sundus, Khalid, Ramsha, Majeed, Abdul, Imran, Imran, Saeed, Hamid, Usman, Muhammad, Ali, Mohsin, Alali, Amer S., AlAsmari, Abdullah F., Ali, Nemat, Asiri, Ali Mohammed, Alasmari, Fawaz, Alqahtani, Faleh
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060346/
https://ncbi.nlm.nih.gov/pubmed/33883647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88154-2
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