Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD

BACKGROUND: Lower airway bacterial colonisation (LABC) in COPD patients is associated with increased exacerbation frequency and faster lung function decline. Defective macrophage phagocytosis in COPD drives inflammation, but how defective macrophage function contributes to exacerbations is not clear...

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Bibliografski detalji
Izdano u:Respir Res
Glavni autori: Singh, R., Belchamber, K. B. R., Fenwick, P. S., Chana, K., Donaldson, G., Wedzicha, J. A., Barnes, P. J., Donnelly, L. E.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059282/
https://ncbi.nlm.nih.gov/pubmed/33879129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01718-8
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