Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD

BACKGROUND: Lower airway bacterial colonisation (LABC) in COPD patients is associated with increased exacerbation frequency and faster lung function decline. Defective macrophage phagocytosis in COPD drives inflammation, but how defective macrophage function contributes to exacerbations is not clear...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Singh, R., Belchamber, K. B. R., Fenwick, P. S., Chana, K., Donaldson, G., Wedzicha, J. A., Barnes, P. J., Donnelly, L. E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059282/
https://ncbi.nlm.nih.gov/pubmed/33879129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01718-8
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