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A predictive coarse-grained model for position-specific effects of post-translational modifications

Biomolecules undergo liquid-liquid phase separation (LLPS), resulting in the formation of multicomponent protein-RNA membraneless organelles in cells. However, the physiological and pathological role of post-translational modifications (PTMs) on the biophysics of phase behavior is only beginning to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Perdikari, Theodora Myrto, Jovic, Nina, Dignon, Gregory L., Kim, Young C., Fawzi, Nicolas L., Mittal, Jeetain
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059201/
https://ncbi.nlm.nih.gov/pubmed/33582133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.01.034
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