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Sequence determinants of protein phase behavior from a coarse-grained model
Membraneless organelles important to intracellular compartmentalization have recently been shown to comprise assemblies of proteins which undergo liquid-liquid phase separation (LLPS). However, many proteins involved in this phase separation are at least partially disordered. The molecular mechanism...
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| Udgivet i: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798848/ https://ncbi.nlm.nih.gov/pubmed/29364893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005941 |
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