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Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration

mRNA transport in neurons requires formation of transport granules containing many protein components, and subsequent alterations in phosphorylation status can release transcripts for translation. Further, mutations in a structurally disordered domain of the transport granule protein hnRNPA2 increas...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Ryan, Veronica H, Perdikari, Theodora M, Naik, Mandar T, Saueressig, Camillo F, Lins, Jeremy, Dignon, Gregory L, Mittal, Jeetain, Hart, Anne C, Fawzi, Nicolas L
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849316/
https://ncbi.nlm.nih.gov/pubmed/33349959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105001
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