Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration

Lignende værker

• Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation
  af: Clarke, Joseph-Patrick W. E., et al.
  Udgivet: (2021)
• Mechanistic view of hnRNPA2 low complexity domain structure, interactions, and phase separation altered by disease mutation and arginine methylation
  af: Ryan, Veronica H., et al.
  Udgivet: (2018)
• Disease mutations in the prion-like domains of hnRNPA1 and hnRNPA2/B1 introduce potent steric zippers that drive excess RNP granule assembly
  af: Shorter, James, et al.
  Udgivet: (2013)
• Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid–liquid phase separation and aggregation
  af: Ryan, Veronica H, et al.
  Udgivet: (2020)
• Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
  af: Gui, Xinrui, et al.
  Udgivet: (2019)