ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM

Metabolic reprogramming, especially Warburg effect, is a key event in tumor initiation and progression. ZEB1 plays a vital role in metastasis of various cancers. We previously found that ZEB1 was excessively expressed in hepatocellular carcinoma (HCC) and its high expression was closely correlated w...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Zhou, Yanming, Lin, Furong, Wan, Tao, Chen, Ai, Wang, Huihui, Jiang, Bin, Zhao, Wentao, Liao, Shan, Wang, Shijie, Li, Guannan, Xu, Zhenzhen, Wang, Jinyang, Zhang, Jia, Ma, Huanhuan, Lin, Donghai, Li, Qinxi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2021
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058737/
https://ncbi.nlm.nih.gov/pubmed/33897890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.56490
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