The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca(2+) Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors

NMDA receptors are ligand-gated ion channels that mediate a slow, Ca(2+)-permeable component of excitatory synaptic currents. These receptors are involved in several important brain functions, including learning and memory, and have also been implicated in neuropathological conditions and acute cent...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Pharmacol
Main Authors: Perszyk, Riley E., Zheng, Zhaoshi, Banke, Tue G., Zhang, Jing, Xie, Lingling, McDaniel, Miranda J., Katzman, Brooke M., Pelly, Stephen C., Yuan, Hongjie, Liotta, Dennis C., Traynelis, Stephen F.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2021
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058507/
https://ncbi.nlm.nih.gov/pubmed/33688039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000218
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