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The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca(2+) Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
NMDA receptors are ligand-gated ion channels that mediate a slow, Ca(2+)-permeable component of excitatory synaptic currents. These receptors are involved in several important brain functions, including learning and memory, and have also been implicated in neuropathological conditions and acute cent...
Sparad:
| I publikationen: | Mol Pharmacol |
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| Huvudupphovsmän: | , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8058507/ https://ncbi.nlm.nih.gov/pubmed/33688039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000218 |
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