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The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca(2+) Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
NMDA receptors are ligand-gated ion channels that mediate a slow, Ca(2+)-permeable component of excitatory synaptic currents. These receptors are involved in several important brain functions, including learning and memory, and have also been implicated in neuropathological conditions and acute cent...
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| Publicado no: | Mol Pharmacol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8058507/ https://ncbi.nlm.nih.gov/pubmed/33688039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000218 |
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