TET-dependent GDF7 hypomethylation impairs aqueous humor outflow and serves as a potential therapeutic target in glaucoma

Glaucoma is the leading cause of irreversible vision loss, affecting more than 70 million individuals worldwide. Circulatory disturbances of aqueous humor (AH) have long been central pathological contributors to glaucomatous lesions. Thus, targeting the AH outflow is a promising approach to treat gl...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Wan, Peixing, Long, Erping, Li, Zhidong, Zhu, Yingting, Su, Wenru, Zhuo, Yehong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2021
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058441/
https://ncbi.nlm.nih.gov/pubmed/33388417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.12.030
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