Trimetazidine protects retinal ganglion cells from acute glaucoma via the Nrf2/Ho-1 pathway

Acute glaucoma is one of the leading causes of irreversible vision impairment characterized by the rapid elevation of intraocular pressure (IOP) and consequent retinal ganglion cell (RGC) death. Oxidative stress and neuroinflammation have been considered critical for the pathogenesis of RGC death in...

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Vydáno v:Clin Sci (Lond)
Hlavní autoři: Wan, Peixing, Su, Wenru, Zhang, Yingying, Li, Zhidong, Deng, Caibin, Zhuo, Yehong
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582167/
https://ncbi.nlm.nih.gov/pubmed/28811386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20171182
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