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Identification and Characterization of Zika Virus NS5 Methyltransferase Inhibitors

The recurring outbreak of Zika virus (ZIKV) worldwide makes an emergent demand for novel, safe and efficacious anti-ZIKV agents. ZIKV non-structural protein 5 (NS5) methyltransferase (MTase), which is essential for viral replication, is regarded as a potential drug target. In our study, a luminescen...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Song, Weibao, Zhang, Hongjuan, Zhang, Yu, Chen, Ying, Lin, Yuan, Han, Yanxing, Jiang, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058401/
https://ncbi.nlm.nih.gov/pubmed/33898335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.665379
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