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Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication

The spread of Zika virus (ZIKV) has caused an international health emergency due to its ability to cause microcephaly in infants. Yet, our knowledge of how ZIKV replicates at the molecular level is limited. For example, how the non-structural protein 5 (NS5) performs replication, and in particular w...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Rusanov, Timur, Kent, Tatiana, Saeed, Mohsan, Hoang, Trung M., Thomas, Crystal, Rice, Charles M., Pomerantz, Richard T.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255901/
https://ncbi.nlm.nih.gov/pubmed/30478404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35511-3
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