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Micro Freeze-Dryer and Infrared-Based PAT: Novel Tools for Primary Drying Design Space Determination of Freeze-Drying Processes

PURPOSE: Present (i) an infrared (IR)-based Process Analytical Technology (PAT) installed in a lab-scale freeze-dryer and (ii) a micro freeze-dryer (MicroFD®) as effective tools for freeze-drying design space calculation of the primary drying stage. METHODS: The case studies investigated are the fre...

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Detalles Bibliográficos
Publicado en:Pharm Res
Main Authors: Harguindeguy, Maitê, Fissore, Davide
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057969/
https://ncbi.nlm.nih.gov/pubmed/33686561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-021-03023-x
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