Investigation of Design Space for Freeze-Drying: Use of Modeling for Primary Drying Segment of a Freeze-Drying Cycle

In this work, we explore the idea of using mathematical models to build design space for the primary drying portion of freeze-drying process. We start by defining design space for freeze-drying, followed by defining critical quality attributes and critical process parameters. Then using mathematical...

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Detalhes bibliográficos
Main Authors: Koganti, Venkat Rao, Shalaev, Evgenyi Y., Berry, Mark R., Osterberg, Thomas, Youssef, Maickel, Hiebert, David N., Kanka, Frank A., Nolan, Martin, Barrett, Rosemary, Scalzo, Gioval, Fitzpatrick, Gillian, Fitzgibbon, Niall, Luthra, Sumit, Zhang, Liling
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167267/
https://ncbi.nlm.nih.gov/pubmed/21710335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9645-7
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