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Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity
Lymphatic endothelial cells (LECs) present peripheral tissue antigens to induce T cell tolerance. In addition, LECs are the main source of sphingosine-1-phosphate (S1P), promoting naive T cell survival and effector T cell exit from lymph nodes (LNs). Autophagy is a physiological process essential fo...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8056750/ https://ncbi.nlm.nih.gov/pubmed/33861848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201776 |
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