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IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity

Plasmacytoid dendritic cells (pDCs) have been shown to both mediate and prevent autoimmunity, and the regulation of their immunogenic versus tolerogenic functions remains incompletely understood. Here we demonstrate that, compared to other cells, pDCs are the major expressors of Indoleamine-2,3-diox...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Lippens, Carla, Duraes, Fernanda V., Dubrot, Juan, Brighouse, Dale, Lacroix, Mathilde, Irla, Magali, Aubry-Lachainaye, Jean-Pierre, Reith, Walter, Mandl, Judith N., Hugues, Stéphanie
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127883/
https://ncbi.nlm.nih.gov/pubmed/27470005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.07.004
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