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A flexible ChIP-sequencing simulation toolkit
BACKGROUND: A major challenge in evaluating quantitative ChIP-seq analyses, such as peak calling and differential binding, is a lack of reliable ground truth data. Accurate simulation of ChIP-seq data can mitigate this challenge, but existing frameworks are either too cumbersome to apply genome-wide...
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| Publié dans: | BMC Bioinformatics |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8056602/ https://ncbi.nlm.nih.gov/pubmed/33879052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04097-5 |
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