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A flexible ChIP-sequencing simulation toolkit

BACKGROUND: A major challenge in evaluating quantitative ChIP-seq analyses, such as peak calling and differential binding, is a lack of reliable ground truth data. Accurate simulation of ChIP-seq data can mitigate this challenge, but existing frameworks are either too cumbersome to apply genome-wide...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Zheng, An, Lamkin, Michael, Qiu, Yutong, Ren, Kevin, Goren, Alon, Gymrek, Melissa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056602/
https://ncbi.nlm.nih.gov/pubmed/33879052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04097-5
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