Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

BACKGROUND: Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer’s disease (AD). This work aimed to determine if and when distribution volume ratio (DVR; derived from dynamic...

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書誌詳細
出版年:Alzheimers Res Ther
主要な著者: Lopes Alves, Isadora, Heeman, Fiona, Collij, Lyduine E., Salvadó, Gemma, Tolboom, Nelleke, Vilor-Tejedor, Natàlia, Markiewicz, Pawel, Yaqub, Maqsood, Cash, David, Mormino, Elizabeth C., Insel, Philip S., Boellaard, Ronald, van Berckel, Bart N. M., Lammertsma, Adriaan A., Barkhof, Frederik, Gispert, Juan Domingo
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056524/
https://ncbi.nlm.nih.gov/pubmed/33875021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00819-2
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