Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

BACKGROUND: Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer’s disease (AD). This work aimed to determine if and when distribution volume ratio (DVR; derived from dynamic...

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Bibliografiset tiedot
Julkaisussa:Alzheimers Res Ther
Päätekijät: Lopes Alves, Isadora, Heeman, Fiona, Collij, Lyduine E., Salvadó, Gemma, Tolboom, Nelleke, Vilor-Tejedor, Natàlia, Markiewicz, Pawel, Yaqub, Maqsood, Cash, David, Mormino, Elizabeth C., Insel, Philip S., Boellaard, Ronald, van Berckel, Bart N. M., Lammertsma, Adriaan A., Barkhof, Frederik, Gispert, Juan Domingo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2021
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056524/
https://ncbi.nlm.nih.gov/pubmed/33875021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00819-2
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