Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

BACKGROUND: Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer’s disease (AD). This work aimed to determine if and when distribution volume ratio (DVR; derived from dynamic...

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Bibliografske podrobnosti
izdano v:Alzheimers Res Ther
Main Authors: Lopes Alves, Isadora, Heeman, Fiona, Collij, Lyduine E., Salvadó, Gemma, Tolboom, Nelleke, Vilor-Tejedor, Natàlia, Markiewicz, Pawel, Yaqub, Maqsood, Cash, David, Mormino, Elizabeth C., Insel, Philip S., Boellaard, Ronald, van Berckel, Bart N. M., Lammertsma, Adriaan A., Barkhof, Frederik, Gispert, Juan Domingo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056524/
https://ncbi.nlm.nih.gov/pubmed/33875021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00819-2
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