Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

BACKGROUND: Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer’s disease (AD). This work aimed to determine if and when distribution volume ratio (DVR; derived from dynamic...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Lopes Alves, Isadora, Heeman, Fiona, Collij, Lyduine E., Salvadó, Gemma, Tolboom, Nelleke, Vilor-Tejedor, Natàlia, Markiewicz, Pawel, Yaqub, Maqsood, Cash, David, Mormino, Elizabeth C., Insel, Philip S., Boellaard, Ronald, van Berckel, Bart N. M., Lammertsma, Adriaan A., Barkhof, Frederik, Gispert, Juan Domingo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056524/
https://ncbi.nlm.nih.gov/pubmed/33875021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00819-2
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