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Simulating the effect of cerebral blood flow changes on regional quantification of [(18)F]flutemetamol and [(18)F]florbetaben studies

Global and regional changes in cerebral blood flow (CBF) can result in biased quantitative estimates of amyloid load by PET imaging. Therefore, the current simulation study assessed effects of these changes on amyloid quantification using a reference tissue approach for [(18)F]flutemetamol and [(18)...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Heeman, Fiona, Yaqub, Maqsood, Lopes Alves, Isadora, Heurling, Kerstin, Bullich, Santiago, Gispert, Juan D, Boellaard, Ronald, Lammertsma, Adriaan A
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907983/
https://ncbi.nlm.nih.gov/pubmed/32281514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20918029
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