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Simulating the effect of cerebral blood flow changes on regional quantification of [(18)F]flutemetamol and [(18)F]florbetaben studies

Global and regional changes in cerebral blood flow (CBF) can result in biased quantitative estimates of amyloid load by PET imaging. Therefore, the current simulation study assessed effects of these changes on amyloid quantification using a reference tissue approach for [(18)F]flutemetamol and [(18)...

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Publicado en:J Cereb Blood Flow Metab
Autores principales: Heeman, Fiona, Yaqub, Maqsood, Lopes Alves, Isadora, Heurling, Kerstin, Bullich, Santiago, Gispert, Juan D, Boellaard, Ronald, Lammertsma, Adriaan A
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907983/
https://ncbi.nlm.nih.gov/pubmed/32281514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20918029
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