Simulating the effect of cerebral blood flow changes on regional quantification of [(18)F]flutemetamol and [(18)F]florbetaben studies

Global and regional changes in cerebral blood flow (CBF) can result in biased quantitative estimates of amyloid load by PET imaging. Therefore, the current simulation study assessed effects of these changes on amyloid quantification using a reference tissue approach for [(18)F]flutemetamol and [(18)...

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Bibliografiske detaljer
Udgivet i:J Cereb Blood Flow Metab
Main Authors: Heeman, Fiona, Yaqub, Maqsood, Lopes Alves, Isadora, Heurling, Kerstin, Bullich, Santiago, Gispert, Juan D, Boellaard, Ronald, Lammertsma, Adriaan A
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907983/
https://ncbi.nlm.nih.gov/pubmed/32281514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20918029
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