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Enhancement and Imputation of Peak Signal Enables Accurate Cell-Type Classification in scATAC-seq
Single-cell Assay Transposase Accessible Chromatin sequencing (scATAC-seq) has been widely used in profiling genome-wide chromatin accessibility in thousands of individual cells. However, compared with single-cell RNA-seq, the peaks of scATAC-seq are much sparser due to the lower copy numbers (diplo...
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| Publicado no: | Front Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8056015/ https://ncbi.nlm.nih.gov/pubmed/33889181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.658352 |
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