Building gene regulatory networks from scATAC-seq and scRNA-seq using Linked Self Organizing Maps

Rapid advances in single-cell assays have outpaced methods for analysis of those data types. Different single-cell assays show extensive variation in sensitivity and signal to noise levels. In particular, scATAC-seq generates extremely sparse and noisy datasets. Existing methods developed to analyze...

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Udgivet i:PLoS Comput Biol
Main Authors: Jansen, Camden, Ramirez, Ricardo N., El-Ali, Nicole C., Gomez-Cabrero, David, Tegner, Jesper, Merkenschlager, Matthias, Conesa, Ana, Mortazavi, Ali
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855564/
https://ncbi.nlm.nih.gov/pubmed/31682608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006555
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