GAMER-MRI in Multiple Sclerosis Identifies the Diffusion-Based Microstructural Measures That Are Most Sensitive to Focal Damage: A Deep-Learning-Based Analysis and Clinico-Biological Validation

Conventional magnetic resonance imaging (cMRI) in multiple sclerosis (MS) patients provides measures of focal brain damage and activity, which are fundamental for disease diagnosis, prognosis, and the evaluation of response to therapy. However, cMRI is insensitive to the damage to the microenvironme...

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Vydáno v:Front Neurosci
Hlavní autoři: Lu, Po-Jui, Barakovic, Muhamed, Weigel, Matthias, Rahmanzadeh, Reza, Galbusera, Riccardo, Schiavi, Simona, Daducci, Alessandro, La Rosa, Francesco, Bach Cuadra, Meritxell, Sandkühler, Robin, Kuhle, Jens, Kappos, Ludwig, Cattin, Philippe, Granziera, Cristina
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055933/
https://ncbi.nlm.nih.gov/pubmed/33889069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.647535
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