GAMER-MRI in Multiple Sclerosis Identifies the Diffusion-Based Microstructural Measures That Are Most Sensitive to Focal Damage: A Deep-Learning-Based Analysis and Clinico-Biological Validation

Conventional magnetic resonance imaging (cMRI) in multiple sclerosis (MS) patients provides measures of focal brain damage and activity, which are fundamental for disease diagnosis, prognosis, and the evaluation of response to therapy. However, cMRI is insensitive to the damage to the microenvironme...

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Опубликовано в: :Front Neurosci
Главные авторы: Lu, Po-Jui, Barakovic, Muhamed, Weigel, Matthias, Rahmanzadeh, Reza, Galbusera, Riccardo, Schiavi, Simona, Daducci, Alessandro, La Rosa, Francesco, Bach Cuadra, Meritxell, Sandkühler, Robin, Kuhle, Jens, Kappos, Ludwig, Cattin, Philippe, Granziera, Cristina
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055933/
https://ncbi.nlm.nih.gov/pubmed/33889069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.647535
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