GAMER-MRI in Multiple Sclerosis Identifies the Diffusion-Based Microstructural Measures That Are Most Sensitive to Focal Damage: A Deep-Learning-Based Analysis and Clinico-Biological Validation

Conventional magnetic resonance imaging (cMRI) in multiple sclerosis (MS) patients provides measures of focal brain damage and activity, which are fundamental for disease diagnosis, prognosis, and the evaluation of response to therapy. However, cMRI is insensitive to the damage to the microenvironme...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Neurosci
Prif Awduron: Lu, Po-Jui, Barakovic, Muhamed, Weigel, Matthias, Rahmanzadeh, Reza, Galbusera, Riccardo, Schiavi, Simona, Daducci, Alessandro, La Rosa, Francesco, Bach Cuadra, Meritxell, Sandkühler, Robin, Kuhle, Jens, Kappos, Ludwig, Cattin, Philippe, Granziera, Cristina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055933/
https://ncbi.nlm.nih.gov/pubmed/33889069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.647535
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