GAMER-MRI in Multiple Sclerosis Identifies the Diffusion-Based Microstructural Measures That Are Most Sensitive to Focal Damage: A Deep-Learning-Based Analysis and Clinico-Biological Validation

Conventional magnetic resonance imaging (cMRI) in multiple sclerosis (MS) patients provides measures of focal brain damage and activity, which are fundamental for disease diagnosis, prognosis, and the evaluation of response to therapy. However, cMRI is insensitive to the damage to the microenvironme...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Lu, Po-Jui, Barakovic, Muhamed, Weigel, Matthias, Rahmanzadeh, Reza, Galbusera, Riccardo, Schiavi, Simona, Daducci, Alessandro, La Rosa, Francesco, Bach Cuadra, Meritxell, Sandkühler, Robin, Kuhle, Jens, Kappos, Ludwig, Cattin, Philippe, Granziera, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055933/
https://ncbi.nlm.nih.gov/pubmed/33889069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.647535
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