Modeling retinitis pigmentosa through patient-derived retinal organoids

Human-induced pluripotent stem cells (hiPSCs) can be differentiated into well-structured retinal organoids. In this protocol, we successfully established 3D retinae from patient-derived hiPSCs and built the retinitis pigmentosa model in vitro. Moreover, mutation in the retinitis pigmentosa GTPase re...

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Bibliografiske detaljer
Udgivet i:STAR Protoc
Main Authors: Li, Yan-Ping, Deng, Wen-Li, Jin, Zi-Bing
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
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Protocol
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055708/
https://ncbi.nlm.nih.gov/pubmed/33899019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100438
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