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Modeling human retinoblastoma using embryonic stem cell-derived retinal organoids
Retinoblastoma (Rb) is the most prevalent intraocular malignancy in early childhood. Traditional models are unable to accurately recapitulate the origin and development of human Rb. Here, we present a protocol to establish a novel human Rb organoid (hRBO) model derived from genetically engineered hu...
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| Publicado en: | STAR Protoc |
|---|---|
| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8058612/ https://ncbi.nlm.nih.gov/pubmed/33899024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100444 |
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