Germline variants at SOHLH2 influence multiple myeloma risk

Multiple myeloma (MM) is caused by the uncontrolled, clonal expansion of plasma cells. While there is epidemiological evidence for inherited susceptibility, the molecular basis remains incompletely understood. We report a genome-wide association study totalling 5,320 cases and 422,289 controls from...

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Gepubliceerd in:Blood Cancer J
Hoofdauteurs: Duran-Lozano, Laura, Thorleifsson, Gudmar, Lopez de Lapuente Portilla, Aitzkoa, Niroula, Abhishek, Went, Molly, Thodberg, Malte, Pertesi, Maroulio, Ajore, Ram, Cafaro, Caterina, Olason, Pall I., Stefansdottir, Lilja, Bragi Walters, G., Halldorsson, Gisli H., Turesson, Ingemar, Kaiser, Martin F., Weinhold, Niels, Abildgaard, Niels, Andersen, Niels Frost, Mellqvist, Ulf-Henrik, Waage, Anders, Juul-Vangsted, Annette, Thorsteinsdottir, Unnur, Hansson, Markus, Houlston, Richard, Rafnar, Thorunn, Stefansson, Kari, Nilsson, Björn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055668/
https://ncbi.nlm.nih.gov/pubmed/33875642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-021-00468-6
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