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In vitro-Constructed Ribosomes Enable Multi-site Incorporation of Noncanonical Amino Acids into Proteins

Efforts to expand the scope of ribosome-mediated polymerization to incorporate noncanonical amino acids (ncAAs) into peptides and proteins hold promise for creating new classes of enzymes, therapeutics, and materials. Recently, the integrated synthesis, assembly, and translation (iSAT) system was es...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Liu, Yi, Davis, Roderick G., Thomas, Paul M., Kelleher, Neil L., Jewett, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055168/
https://ncbi.nlm.nih.gov/pubmed/33426883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00829
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