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Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma
Glioma stem-like cells dynamically transition between a chemoradiation-resistant state (preferentially in the perivascular niche) and a chemoradiation-sensitive state (away from blood vessels). However, physical barriers in the tumour microenvironment restrict the delivery of chemotherapy to tumour...
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| Published in: | Nat Biomed Eng |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054983/ https://ncbi.nlm.nih.gov/pubmed/33864039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-021-00710-3 |
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