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T Cell Receptor Engineered Lymphocytes for Cancer Therapy

T lymphocytes are capable of specific recognition and elimination of target cells. Physiological antigen recognition is mediated by the T cell receptor (TCR), which is an alpha beta heterodimer comprising the products of randomly rearranged V, D, and J genes. The exquisite specificity and functional...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Protoc Immunol
Hauptverfasser: Rollins, Meagan R., Spartz, Ellen J., Stromnes, Ingunn M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054879/
https://ncbi.nlm.nih.gov/pubmed/32432843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpim.97
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