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New Strategies in Engineering T-Cell Receptor Gene-Modified T Cells to More Effectively Target Malignancies

The immune system, and T cells in particular, have the ability to target and destroy malignant cells. However, anti-tumor immune responses induced from the endogenous T cell repertoire are often insufficient for the eradication of established tumors, as illustrated by the failure of cancer vaccinati...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Schmitt, Thomas M., Stromnes, Ingunn M., Chapuis, Aude G., Greenberg, Philip D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746077/
https://ncbi.nlm.nih.gov/pubmed/26463711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0860
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