CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer

BACKGROUND: Cisplatin (CDDP) has become a standard-of-care treatment for muscle-invasive bladder cancer (MIBC), while chemoresistance remains a major challenge. Accumulating evidence indicates that circular RNAs (circRNAs) are discrete functional entities. However, the regulatory functions as well a...

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Publicado en:Mol Cancer
Autores principales: Zhang, Hui, Xiao, Xingyuan, Wei, Wenjie, Huang, Chao, Wang, Miao, Wang, Liang, He, Yuanqiao, Sun, Jiayin, Jiang, Yangkai, Jiang, Guosong, Zhang, Xiaoping
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054397/
https://ncbi.nlm.nih.gov/pubmed/33874956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-021-01360-4
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