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Deciphering the Mismatch Recognition Cycle in MutS and MSH2-MSH6 Using Normal-Mode Analysis

Postreplication DNA mismatch repair is essential for maintaining the integrity of genomic information in prokaryotes and eukaryotes. The first step in mismatch repair is the recognition of base-base mismatches and insertions/deletions by bacterial MutS or eukaryotic MSH2-MSH6. Crystal structures of...

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Detalhes bibliográficos
Main Authors: Mukherjee, Shayantani, Law, Sean M., Feig, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325129/
https://ncbi.nlm.nih.gov/pubmed/19254532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.071
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