Base-Flipping Mechanism in Postmismatch Recognition by MutS

DNA mismatch recognition and repair is vital for preserving the fidelity of the genome. Conserved across prokaryotes and eukaryotes, MutS is the primary protein that is responsible for recognizing a variety of DNA mismatches. From molecular dynamics simulations of the Escherichia coli MutS-DNA compl...

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Bibliographic Details
Main Authors: Law, Sean M., Feig, Michael
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2011
Subjects:
Nucleic Acid
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207177/
https://ncbi.nlm.nih.gov/pubmed/22067162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.045
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