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Differential Mismatch Recognition Specificities of Eukaryotic MutS Homologs, MutSα and MutSβ
In eukaryotes, the recognition of the DNA postreplication errors and initiation of the mismatch repair is carried out by two MutS homologs: MutSα and MutSβ. MutSα recognizes base mismatches and 1 to 2 unpaired nucleotides whereas MutSβ recognizes longer insertion-deletion loops (IDLs) with 1 to 15 u...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052273/ https://ncbi.nlm.nih.gov/pubmed/24896128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.026 |
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