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Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut
The bacterium Clostridium perfringens causes severe, sometimes lethal gastrointestinal disorders in humans, including enteritis and enterotoxemia. Type F strains produce an enterotoxin (CpE) that causes the third most common foodborne illness in the United States. CpE induces gut breakdown by disrup...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8053971/ https://ncbi.nlm.nih.gov/pubmed/33876770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024651118 |
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